OR51F2

OR51F2 is a gene that encodes a protein in the olfactory receptor family. This family is a group of G protein-coupled receptors which are responsible for detecting molecules in the environment and subsequently initiating a neuronal response. The olfactory receptor proteins interact with odorant molecules in the nose to initiate a neuronal response that triggers the perception of a smell.

Function

The olfactory receptor family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. The function of OR51F2, like many other olfactory receptors, is primarily related to the detection of environmental chemicals, contributing to the sense of smell.

Structure

The OR51F2 gene is located on chromosome 11, specifically at 11q11. It spans approximately 1.1 kilobases and consists of a single exon. The OR51F2 protein it encodes is a member of the olfactory receptor family, which is a subset of the class A rhodopsin-like family of G protein-coupled receptors.

Clinical Significance

While the specific clinical significance of OR51F2 is not yet fully understood, olfactory receptors in general have been implicated in various diseases and conditions. For example, mutations in olfactory receptors have been associated with a decreased sense of smell, known as anosmia. Further research is needed to determine the specific role of OR51F2 in health and disease.

See Also

• Olfactory receptor
• G protein-coupled receptor
• Anosmia