OR51I1
OR51I1 is a gene that encodes a protein in humans and is part of the olfactory receptor family. The olfactory receptor family is the largest in the genome. The family members are G-protein coupled receptors that respond to odor molecules and are responsible for our sense of smell.
Function[edit | edit source]
The OR51I1 gene is thought to have a role in the detection of odorants. It is expressed in the olfactory epithelium, a specialized tissue inside the nose that is involved in smell. The protein that OR51I1 encodes is a member of the olfactory receptor family, which is a group of proteins that detect smells and send signals to the brain.
Structure[edit | edit source]
The OR51I1 gene is located on chromosome 11 in humans. The protein it encodes is a member of the G protein-coupled receptor superfamily. This family of proteins has a characteristic structure with seven transmembrane domains.
Clinical significance[edit | edit source]
While the exact role of OR51I1 in disease is not fully understood, it is thought that changes in the function or expression of olfactory receptors like OR51I1 could potentially contribute to conditions such as anosmia (loss of smell) or hyposmia (reduced ability to smell).
See also[edit | edit source]
References[edit | edit source]
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Contributors: Prab R. Tumpati, MD