OR51I2

From WikiMD's Food, Medicine & Wellness Encyclopedia

OR51I2 is a gene that encodes the olfactory receptor protein, OR51I2. This protein is a member of the olfactory receptor family, which is involved in the detection of smell. The OR51I2 gene is located on chromosome 11 in humans.

Function[edit | edit source]

The olfactory receptor proteins, such as OR51I2, are responsible for detecting and identifying a wide range of odors. These proteins are located in the olfactory epithelium, a specialized tissue inside the nose that is involved in smell. When an odor molecule binds to an olfactory receptor, it triggers a signal that is sent to the brain, allowing us to perceive the smell.

Structure[edit | edit source]

The OR51I2 protein is a G protein-coupled receptor (GPCR), which is a type of protein that spans the cell membrane and is involved in signal transduction. The structure of GPCRs is characterized by seven transmembrane domains, which are regions of the protein that span the cell membrane. The OR51I2 protein, like other olfactory receptors, has a specific binding site for odor molecules.

Clinical significance[edit | edit source]

While the primary function of the OR51I2 gene is in the detection of smell, research has suggested that it may also play a role in other physiological processes. For example, some studies have suggested that OR51I2 may be involved in the regulation of apoptosis, a process of programmed cell death that is important in development and disease.

See also[edit | edit source]

References[edit | edit source]



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Contributors: Prab R. Tumpati, MD