OR52E2

OR52E2 is a gene that encodes a protein in humans. It is also known as olfactory receptor family 52 subfamily E member 2. The OR52E2 gene is part of the olfactory receptor gene family, which is the largest gene family in the genome. The family members are G-protein coupled receptors that respond to smell and taste stimuli and are divided into a main group, intermediate group, and several outlier groups.

Function

The OR52E2 gene is a member of the olfactory receptor family of genes. Olfactory receptors are responsible for the detection of odor molecules in the nose, which leads to the sense of smell. The OR52E2 gene encodes a protein that is thought to be involved in this process.

Structure

The OR52E2 gene is located on chromosome 11 in humans. It spans approximately 1 kilobase and consists of a single exon. The OR52E2 protein is a member of the class A rhodopsin-like family of G-protein coupled receptors.

Clinical significance

Mutations in the OR52E2 gene have been associated with a reduced sense of smell, known as anosmia. This condition can be either congenital (present from birth) or acquired later in life.

Research

Research into the OR52E2 gene and its associated protein is ongoing. Scientists are particularly interested in understanding how mutations in this gene may contribute to conditions such as anosmia and other olfactory disorders.