OR52E4

From WikiMD's Wellness Encyclopedia

OR52E4 is a gene that encodes a protein in humans. It is part of the olfactory receptor family, a group of genes that are involved in the detection of smell. The OR52E4 gene is located on chromosome 11.

Function[edit | edit source]

The OR52E4 gene encodes a protein that is a member of the olfactory receptor family. These receptors are located in the olfactory epithelium, a specialized tissue inside the nose that is involved in smell. The receptors bind to odor molecules, triggering a nerve impulse that is sent to the brain. This allows us to detect and identify different smells.

Structure[edit | edit source]

Like other olfactory receptors, the protein encoded by the OR52E4 gene is a G protein-coupled receptor. This means it spans the cell membrane seven times and is coupled to a G protein, which transmits signals from the receptor to the inside of the cell. The specific structure of the OR52E4 protein, including the arrangement of its seven transmembrane domains, is not yet fully understood.

Clinical significance[edit | edit source]

While the exact role of the OR52E4 gene in human health and disease is not yet fully understood, it is thought that variations in this gene may be associated with differences in smell perception. Further research is needed to fully understand the clinical significance of this gene.

See also[edit | edit source]


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Contributors: Prab R. Tumpati, MD