OR56B4

OR56B4 is a gene that encodes a protein in humans. This gene is also known as olfactory receptor 56B4. Olfactory receptors, such as OR56B4, form a part of the olfactory system, which is responsible for the sense of smell.

Function

The OR56B4 gene belongs to the family of olfactory receptor genes, which are the largest gene family in the genome. The olfactory receptors interact with odorant molecules in the nose, initiating a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes.

Gene

The OR56B4 gene is located on the chromosome 11 (11p15.4). It spans around 1,000 base pairs and consists of a single coding exon. The gene is expressed in the olfactory epithelium.

Protein

The protein encoded by the OR56B4 gene is a member of the olfactory receptor family (class A, G-protein coupled receptors). These proteins are responsible for detecting odorants in the nasal cavity and initiating a signal transduction pathway that leads to the perception of smell.

Clinical significance

While the exact role of OR56B4 in disease is not well understood, olfactory receptors in general have been implicated in various diseases, including Parkinson's disease, Alzheimer's disease, and certain types of cancer.

See also

• Olfactory receptor
• Olfactory system
• G protein-coupled receptor
• Chromosome 11

References

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