OR5H2

OR5H2 is a gene that encodes a protein in humans. It is also known as Olfactory Receptor Family 5 Subfamily H Member 2. The OR5H2 gene is part of the olfactory receptor family, which is the largest gene family in the genome. The family members are G-protein coupled receptors that respond to smell and taste stimuli and are responsible for our sense of smell.

Function[edit | edit source]

The OR5H2 gene, like other olfactory receptors, functions as a molecular sensor, detecting different odor molecules in the nose and then sending signals to the brain. This gene is thought to be involved in the perception of specific scents, although the exact scents it responds to are not yet known.

Structure[edit | edit source]

The OR5H2 protein is a member of the G protein-coupled receptor superfamily. This diverse group of proteins contains seven transmembrane domains, which allow them to span the cell membrane and interact with molecules both inside and outside the cell.

Clinical Significance[edit | edit source]

While the exact role of OR5H2 in disease is not yet known, olfactory receptors in general have been implicated in a variety of conditions, including neurodegenerative diseases like Parkinson's disease and Alzheimer's disease, as well as certain types of cancer.

Research[edit | edit source]

Research into the OR5H2 gene and its protein product is ongoing. Scientists are particularly interested in understanding how this and other olfactory receptors contribute to our sense of smell, and how they might be targeted for therapeutic purposes.