OR5M8

OR5M8 is a gene that encodes a protein in humans. This protein is a member of the olfactory receptor family, which is involved in the detection of smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes.

Function

The olfactory receptor proteins are thought to have a role in odorant recognition and are expressed in the olfactory epithelium of the nose. The specific function of the OR5M8 protein, however, is not yet fully understood.

Structure

The OR5M8 gene is located on chromosome 1, specifically at 1q44. The gene spans approximately 1 kilobase and consists of a single coding exon. The encoded protein is a member of the G protein-coupled receptor family, which is characterized by seven transmembrane domains.

Clinical Significance

While the specific clinical significance of OR5M8 is not yet fully understood, olfactory receptors in general have been implicated in various diseases and conditions. For example, mutations in olfactory receptors have been associated with anosmia, a condition characterized by a loss of the sense of smell.

Research

Research into the OR5M8 gene and its encoded protein is ongoing. Understanding the specific function and significance of this gene could have implications for understanding the sense of smell and potentially treating conditions related to olfaction.

See Also

• Olfactory receptor
• G protein-coupled receptor
• Anosmia