OR6B3

From WikiMD's Wellness Encyclopedia

OR6B3 is a gene that encodes the olfactory receptor, family 6, subfamily B, member 3. This gene is part of the olfactory receptor family, which is the largest gene family in the genome. The olfactory receptors are G protein-coupled receptors that are involved in the detection of smell.

Function[edit | edit source]

The OR6B3 gene is responsible for encoding a protein that acts as a receptor for odorant molecules in the nose. This receptor is part of the G protein-coupled receptor family, which is a large group of proteins that play a role in many different physiological functions. The specific function of OR6B3 is to detect and respond to the presence of certain odorant molecules, contributing to the sense of smell.

Structure[edit | edit source]

The OR6B3 gene is located on chromosome 11, and it spans approximately 1 kilobase. The encoded protein is a member of the rhodopsin-like receptors subfamily of G protein-coupled receptors. Like other members of this family, it has seven transmembrane domains and is likely to signal via a G protein.

Clinical significance[edit | edit source]

While the exact role of OR6B3 in disease is not well understood, it is thought that variations in this gene may be associated with differences in individuals' sense of smell. Further research is needed to fully understand the potential clinical significance of this gene.

See also[edit | edit source]

References[edit | edit source]



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Contributors: Prab R. Tumpati, MD