OR6F1
OR6F1 is a gene that encodes a protein in humans. It is also known as olfactory receptor, family 6, subfamily F, member 1. This gene is part of the olfactory receptor gene family, which is the largest gene family in the genome. The olfactory receptors are G protein-coupled receptors that are involved in the detection of smell.
Function[edit | edit source]
The OR6F1 gene is a member of the olfactory receptor family, which is responsible for the detection of odor molecules. The olfactory receptors interact with odorant molecules in the nose, initiating a neural response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein coupled receptors (GPCR) arising from single coding-exon genes.
Structure[edit | edit source]
The OR6F1 gene is located on chromosome 1, specifically at 1q44. It spans a length of approximately 1.1 kb and consists of a single coding exon. The encoded protein has 7 transmembrane domains, which is characteristic of G protein-coupled receptors.
Clinical Significance[edit | edit source]
While the specific role and clinical significance of OR6F1 are not fully understood, olfactory receptors in general are thought to have roles in various physiological and disease processes. These include sperm chemotaxis, the immune response, and cancer. Further research is needed to elucidate the specific roles and potential clinical applications of OR6F1.
See Also[edit | edit source]
References[edit | edit source]
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Contributors: Prab R. Tumpati, MD