OR7A10
OR7A10 is a protein that in humans is encoded by the OR7A10 gene. It is a member of the olfactory receptor family of genes, which are the largest gene family in the genome. The olfactory receptors (ORs) are G protein-coupled receptors that play a role in the detection of odorants.
Function[edit | edit source]
Olfactory receptors function by binding to odor molecules in the nose, initiating a neural response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein coupled receptors (GPCR) arising from single coding-exon genes.
Gene[edit | edit source]
The OR7A10 gene is located on chromosome 19, specifically at 19p13.2. It spans approximately 1 kilobase and consists of a single coding exon. The exact function of this gene is not known, but it is believed to play a role in olfaction.
Protein Structure[edit | edit source]
The OR7A10 protein is a transmembrane protein, meaning it spans the membrane of a cell. It has seven transmembrane domains, which is characteristic of G protein-coupled receptors.
Clinical Significance[edit | edit source]
While the exact role of OR7A10 in human health and disease is not fully understood, olfactory receptors in general are thought to have roles in various diseases such as cancer, neurodegenerative diseases, and infectious diseases.
See Also[edit | edit source]
References[edit | edit source]
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Contributors: Prab R. Tumpati, MD