OR8A1

OR8A1 is a gene that encodes a protein in the olfactory receptor family. This family is a group of G protein-coupled receptors which are responsible for detecting odor molecules in the nose. The OR8A1 gene is specifically involved in the detection of certain odorants.

Function

The OR8A1 gene is part of the olfactory receptor family, a group of genes that are expressed in the olfactory epithelium of the nose. These receptors are responsible for the detection of odor molecules in the air, which are then translated into signals that the brain interprets as specific smells.

The OR8A1 gene encodes a protein that is believed to function as a receptor for specific odorants. This protein is a member of the G protein-coupled receptor superfamily, a large group of proteins that play a role in many different physiological functions.

Structure

The OR8A1 gene is located on chromosome 11 in humans. It spans approximately 1 kilobase and consists of a single exon. The OR8A1 protein is a member of the G protein-coupled receptor superfamily, and like other members of this family, it has seven transmembrane domains.

Clinical significance

While the exact role of the OR8A1 gene in human health and disease is not fully understood, it is believed to play a role in the sense of smell. Mutations in this gene, as well as other genes in the olfactory receptor family, have been associated with a reduced ability to smell, a condition known as anosmia.

See also

• Olfactory receptor
• G protein-coupled receptor
• Anosmia