OR8B2

OR8B2 is a gene that encodes a protein in humans. This protein is part of the olfactory receptor family, a group of proteins that are involved in the detection of smell. The OR8B2 gene is located on chromosome 11.

Function

The olfactory receptor proteins, such as the one encoded by the OR8B2 gene, are located in the cell membranes of olfactory receptor neurons in the nose. These proteins bind to odor molecules, triggering a nerve impulse that is sent to the brain. This process allows us to detect and identify different smells.

Structure

The OR8B2 protein is a member of the G protein-coupled receptor superfamily. This family of proteins has a characteristic structure with seven transmembrane domains. The specific structure of the OR8B2 protein allows it to bind to specific odor molecules.

Clinical significance

While the OR8B2 gene is primarily involved in the sense of smell, mutations in this gene have been associated with certain medical conditions. For example, a decreased sense of smell (known as anosmia) can occur if the OR8B2 gene is not functioning properly.

See also

• Olfactory receptor
• Anosmia
• G protein-coupled receptor