OR8D2

From WikiMD's Wellness Encyclopedia

OR8D2 (Olfactory Receptor Family 8 Subfamily D Member 2) is a protein that in humans is encoded by the OR8D2 gene. This protein is part of the olfactory receptor family, which is involved in the detection of smell.

Function[edit | edit source]

The OR8D2 protein is a member of the olfactory receptor family, a class of G protein-coupled receptors (GPCRs) that are located in the olfactory epithelium in the nose. These receptors are responsible for the detection of odor molecules in the air, which are then translated into signals that the brain interprets as specific smells.

Gene[edit | edit source]

The OR8D2 gene is located on chromosome 11 (11p15.4). It spans approximately 1 kilobase and consists of a single coding exon. The gene is expressed in the olfactory epithelium.

Clinical significance[edit | edit source]

While the exact role of OR8D2 in disease is not fully understood, olfactory receptors in general have been implicated in a variety of conditions, including Parkinson's disease, Alzheimer's disease, and certain types of cancer.

See also[edit | edit source]

References[edit | edit source]


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Contributors: Prab R. Tumpati, MD