OR9Q1

OR9Q1 is a gene that in humans is encoded by the OR9Q1 olfactory receptor family 9 subfamily Q member 1. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

Structure

The OR9Q1 gene is located on chromosome 11, specifically 11p15.4. It spans a length of 1.1 kb and contains 1 exon. The OR9Q1 protein is a member of the GPCR family, which is characterized by 7 transmembrane domains.

Function

The OR9Q1 protein is an olfactory receptor, which is a protein involved in the detection of odor molecules. Olfactory receptors are expressed in the cell membranes of olfactory receptor neurons and are responsible for the detection of odorants in the nose.

Clinical Significance

While the specific clinical significance of OR9Q1 is not yet fully understood, olfactory receptors in general have been implicated in various diseases and conditions. For example, alterations in the sense of smell, known as olfactory dysfunction, can be an early sign of neurodegenerative diseases like Alzheimer's and Parkinson's.

Research Directions

Further research is needed to understand the specific role of OR9Q1 in olfaction and potential implications in disease.

See Also

• Olfactory receptor
• G protein-coupled receptor
• Neurodegenerative diseases