ORG-20599

ORG-20599 is a synthetic steroid that is used in scientific research. It acts as a selective agonist for the peripheral benzodiazepine receptor, also known as the translocator protein (TSPO), and has anxiolytic effects.

Chemistry[edit | edit source]

ORG-20599 is a synthetic steroid, which means it is a man-made compound that mimics the structure and function of naturally occurring steroids in the body. Steroids are a type of organic compound that are characterized by a specific arrangement of four cycloalkane rings that are joined to each other.

Pharmacology[edit | edit source]

As a selective agonist for the peripheral benzodiazepine receptor, ORG-20599 binds to this receptor and activates it. The peripheral benzodiazepine receptor, also known as the translocator protein (TSPO), is found primarily in the mitochondria of steroid-synthesizing tissues, including the adrenal gland and gonads. Activation of this receptor by ORG-20599 can lead to anxiolytic effects, which means it can reduce anxiety.

Research[edit | edit source]

ORG-20599 has been used in scientific research to study the role of the peripheral benzodiazepine receptor in various physiological and pathological processes. For example, it has been used to investigate the role of this receptor in the regulation of steroidogenesis, the process by which steroids are produced in the body. It has also been used to study the potential therapeutic effects of activating this receptor in conditions such as anxiety disorders.

See also[edit | edit source]

ORG-20599 Resources
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