Ocfentanil

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Ocfentanil


Ocfentanil is a potent synthetic opioid that is similar in structure and function to its parent compound, fentanyl. It is an analogue of fentanyl and is approximately 100 times more potent. Ocfentanil is used in medicine for its analgesic effects.

Chemistry[edit | edit source]

Ocfentanil is a synthetic opioid that is structurally related to fentanyl. It is a phenylpiperidine derivative and is chemically described as N-(2-fluorophenyl)-2-methoxy-N-(1-phenethylpiperidin-4-yl)acetamide. The molecular formula of ocfentanil is C22H28FNO2.

Pharmacology[edit | edit source]

Ocfentanil acts primarily on the mu-opioid receptor, producing analgesic and sedative effects. Like other opioids, it also has the potential to cause respiratory depression, nausea, and constipation. The onset of action is rapid, and the duration of action is typically short, making it useful for procedures requiring rapid onset and offset of analgesic effect.

Medical Use[edit | edit source]

In the medical field, ocfentanil is used for its potent analgesic effects. It is often used in anesthesia for procedures that require a high level of analgesia. Due to its potency, it is typically used in a hospital setting under the supervision of trained medical professionals.

Legal Status[edit | edit source]

In many countries, including the United States, ocfentanil is a controlled substance due to its high potential for abuse and addiction. It is classified as a Schedule II drug under the Controlled Substances Act in the United States.

Safety[edit | edit source]

Due to its high potency, ocfentanil carries a significant risk of overdose. Symptoms of overdose can include slow or shallow breathing, severe sleepiness, and loss of consciousness. In the event of an overdose, immediate medical attention is required.

See Also[edit | edit source]




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Contributors: Prab R. Tumpati, MD