Odontoma dysphagia syndrome

From WikiMD's Wellnesspedia


Odontoma dysphagia syndrome (Bader syndrome) is a rare syndrome (<10 cases reported to date) first described in 1967.[1] The cause is not known but it is suspected to be genetic in origin.

Presentation[edit | edit source]

This syndrome is characterized by clustering of teeth (compound odontoma, dysplasia and aplasia of teeth), slight craniofacial abnormalities, and dysphagia. The dysphagia may be due to an over growth of muscle tissue or strictures in the oesophagus. Benign tumors (odontomas) may form at the roots of the teeth.

Cause[edit | edit source]

The cause is thought to be genetic and it may inherited in an autosomal dominant fashion.[2] A possible link to chromosome 11 (11q13.3) a region that included fibroblast growth factors 3 and 4 has been reported.[3]

Treatment[edit | edit source]

References[edit | edit source]

  1. Bader G (1967) Odontomatosis (multiple odontomas). Oral Surg Oral Med OralPathol 23:770
  2. Schönberger W (1974) Multiple odontomas (Odontomatosis) and dysphagia in father and son-a syndromic connection? Z Kinderheilkd 117(2):101-108
  3. Ziebart T, Draenert FG, Galetzka D, Babaryka G, Schmidseder R, Wagner W, Bartsch O (2012) The original family revisited after 37 years: odontoma-dysphagia syndrome is most likely caused by a microduplication of chromosome 11q13.3, including the FGF3 and FGF4 genes. Clin Oral Investig

External links[edit | edit source]

Classification
External resources
Wiki.png

Navigation: Wellness - Encyclopedia - Health topics - Disease Index‏‎ - Drugs - World Directory - Gray's Anatomy - Keto diet - Recipes

Search WikiMD


Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro) available.
Advertise on WikiMD

WikiMD is not a substitute for professional medical advice. See full disclaimer.

Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.


Contributors: Prab R. Tumpati, MD