Olfactory receptor family 2 subfamily ag member 2
Olfactory receptor family 2 subfamily ag member 2 (OR2AG2) is a protein that in humans is encoded by the OR2AG2 gene. This protein is a member of the olfactory receptor family, which is the largest gene family in the genome. Olfactory receptors are G protein-coupled receptors that are involved in the detection of smell.
Function[edit | edit source]
The OR2AG2 protein is an olfactory receptor. Olfactory receptors interact with odorant molecules in the nose to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein coupled receptors (GPCR) arising from single coding-exon genes.
Gene[edit | edit source]
The OR2AG2 gene is located on chromosome 11 (11q11). It spans approximately 1 kilobase and contains one exon. The OR2AG2 gene is a member of the olfactory receptor gene family, which is the largest gene family in the genome.
Clinical significance[edit | edit source]
While the specific clinical significance of OR2AG2 is not yet fully understood, olfactory receptors in general play a crucial role in the sense of smell. Disruptions in the function of these receptors can lead to anosmia, or the inability to perceive odor.
See also[edit | edit source]
References[edit | edit source]
External links[edit | edit source]
- OR2AG2 at the National Center for Biotechnology Information
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Contributors: Prab R. Tumpati, MD