Opisthorchis felineus

From WikiMD's Wellnesspedia

Opisthorchis felineus, also known as the Siberian or feline liver fluke, is a species of trematode parasites primarily affecting the liver and bile ducts of mammals, including humans. This parasitic flatworm is a significant cause of a disease known as opisthorchiasis, which is a major public health concern in some parts of the world, particularly in Eastern Europe and Asia.

Life Cycle[edit | edit source]

The life cycle of Opisthorchis felineus involves three hosts: freshwater snails, fish, and mammals (including humans). The cycle begins when eggs are excreted in the feces of an infected host. Once in freshwater, the eggs hatch into free-swimming larvae (miracidia) that infect specific snail species. Within the snail, the larvae undergo several developmental stages before emerging as cercariae, which then infect freshwater fish by penetrating their skin or gills. When mammals consume raw or undercooked infected fish, the cercariae develop into adult flukes in the bile ducts, completing the cycle.

Transmission[edit | edit source]

Transmission of Opisthorchis felineus to humans primarily occurs through the consumption of raw or undercooked freshwater fish containing infective larvae. Traditional dishes that involve lightly pickled, smoked, or salted fish can be sources of infection if the fish are not properly cooked.

Symptoms and Diagnosis[edit | edit source]

In the early stages of infection, opisthorchiasis may be asymptomatic or present with non-specific symptoms such as abdominal pain, nausea, and diarrhea. Chronic infection can lead to more serious conditions, including cholangitis (inflammation of the bile ducts), cholecystitis (inflammation of the gallbladder), and liver fibrosis. Severe cases may progress to cholangiocarcinoma, a type of bile duct cancer.

Diagnosis of opisthorchiasis typically involves the microscopic examination of stool samples to identify Opisthorchis eggs. Serological tests and imaging techniques such as ultrasound may also be used to assess the extent of infection and organ damage.

Treatment and Prevention[edit | edit source]

Treatment for opisthorchiasis involves the use of antiparasitic medications, with praziquantel being the drug of choice. Preventive measures focus on reducing the risk of transmission, primarily through public health education on the dangers of consuming raw or undercooked fish and improving sanitation to prevent contamination of water bodies with human feces.

Epidemiology[edit | edit source]

Opisthorchis felineus is endemic in certain regions, including parts of Russia, Kazakhstan, Ukraine, and other areas around the Caspian and Baltic Seas. The prevalence of opisthorchiasis in these areas is closely linked to local dietary habits and the consumption of traditional fish dishes.

Research and Public Health Initiatives[edit | edit source]

Research on Opisthorchis felineus and opisthorchiasis focuses on understanding the parasite's life cycle, developing more effective diagnostic methods, and exploring new treatment options. Public health initiatives aim to reduce the incidence of opisthorchiasis through education, improved sanitation, and the promotion of safe food handling practices.

Resources[edit source]

Latest articles - Opisthorchis felineus

PubMed
Clinical trials
UpToDate

AI tools[edit source]

Generative AI tools and links to learn more on Opisthorchis felineus: ChatGPT - Bing Chat - Google Gemini. (caution advised).


Wiki.png

Navigation: Wellness - Encyclopedia - Health topics - Disease Index‏‎ - Drugs - World Directory - Gray's Anatomy - Keto diet - Recipes

Search WikiMD


Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro) available.
Advertise on WikiMD

WikiMD is not a substitute for professional medical advice. See full disclaimer.

Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.


Contributors: Admin, Prab R. Tumpati, MD