Org 28312
Org 28312 is a pharmacological compound that is classified as a serotonin receptor antagonist. It is primarily used in scientific research to study the effects of serotonin on the brain and body.
Overview[edit | edit source]
Org 28312 is a potent and selective antagonist of the 5-HT2A receptor, a subtype of the serotonin receptor. This receptor is found in high concentrations in the cerebral cortex and is thought to play a key role in cognitive functions such as learning and memory. By blocking the activity of this receptor, Org 28312 can be used to investigate the role of serotonin in these processes.
Pharmacology[edit | edit source]
As a 5-HT2A receptor antagonist, Org 28312 works by binding to these receptors and preventing serotonin from activating them. This can help to reduce the effects of excessive serotonin activity, such as those seen in conditions like schizophrenia and depression.
In addition to its effects on the 5-HT2A receptor, Org 28312 also has some activity at other serotonin receptors. However, its effects at these other receptors are generally less potent and less well understood.
Research Applications[edit | edit source]
Org 28312 is primarily used in preclinical research to study the role of the 5-HT2A receptor in various physiological and pathological processes. For example, it has been used to investigate the role of this receptor in the regulation of mood and behavior, the modulation of cognitive functions, and the pathophysiology of psychiatric disorders.
In addition, Org 28312 can also be used as a tool to study the pharmacology of the serotonin system more generally. By comparing the effects of Org 28312 with those of other serotonin receptor antagonists, researchers can gain insights into the relative contributions of different serotonin receptors to various physiological and pathological processes.
See Also[edit | edit source]
 | This pharmacology-related article is a stub. You can help WikiMD by expanding it. |
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
