Osteoporotic bone marrow defect

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Osteoporotic bone marrow defect (OBMD), also known as osteoporotic bone marrow defect, is a medical condition characterized by a decrease in bone strength that increases the risk of a broken bone. It is the most common reason for a broken bone among the elderly.

Overview[edit | edit source]

OBMD is a type of bone disease that occurs when the body loses too much bone, makes too little bone, or both. As a result, bones become weak and may break from a fall or, in serious cases, from sneezing or minor bumps.

Causes[edit | edit source]

The exact cause of OBMD is unknown, but it is believed to be caused by a combination of genetic, dietary, and environmental factors. Risk factors include aging, being female, low body weight, low sex hormones or menopause, smoking, and some medications.

Symptoms[edit | edit source]

OBMD is often called a silent disease because one can’t feel bones weakening. But once your bones have been weakened by osteoporosis, you might have signs and symptoms that include back pain, caused by a fractured or collapsed vertebra, loss of height over time, a stooped posture, or a bone that breaks much more easily than expected.

Diagnosis[edit | edit source]

OBMD is typically diagnosed through a bone density test, which measures the amount of bone mineral in your bones. This test can identify osteoporosis, determine your risk for fractures, and measure your response to osteoporosis treatment.

Treatment[edit | edit source]

Treatment for OBMD includes medication, healthy diet, and weight-bearing exercise to help prevent bone loss or strengthen already weak bones.

See also[edit | edit source]

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Contributors: Prab R. Tumpati, MD