Oxytocin/ergometrine

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Oxytocin/ergometrine is a medication that is commonly used in obstetrics to control postpartum hemorrhage and other bleeding after childbirth. It is a combination of two drugs, oxytocin and ergometrine, which work together to contract the uterus and reduce bleeding.

Etymology[edit | edit source]

The term "oxytocin" comes from the Greek words "oxys" and "tokos", which mean "quick" and "birth" respectively. This is in reference to the drug's ability to speed up labor. The term "ergometrine" is derived from the Greek words "ergon" and "metron", which mean "work" and "uterus" respectively. This is in reference to the drug's ability to stimulate contractions in the uterus.

Pharmacology[edit | edit source]

Oxytocin is a hormone that is naturally produced by the pituitary gland in the brain. It plays a crucial role in childbirth by causing the uterus to contract, which helps to push the baby out. In medicine, synthetic oxytocin is used to induce or speed up labor, and to control bleeding after childbirth.

Ergometrine, on the other hand, is a medication that is derived from a type of fungus known as ergot. It works by stimulating the smooth muscle in the uterus, causing it to contract. This helps to control bleeding after childbirth.

When used together, oxytocin and ergometrine provide a powerful combination for controlling postpartum hemorrhage.

Side Effects[edit | edit source]

Like all medications, oxytocin/ergometrine can cause side effects. These may include nausea, vomiting, abdominal pain, and changes in blood pressure. In rare cases, it can cause severe allergic reactions.

Related Terms[edit | edit source]

Oxytocin/ergometrine Resources
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Contributors: Prab R. Tumpati, MD