P2RY6
P2RY6 is a protein that in humans is encoded by the P2RY6 gene. This protein is a member of the G protein-coupled receptor family, and is a receptor for UDP (Uridine diphosphate) sugars.
Function[edit | edit source]
The P2RY6 gene encodes a member of the purinergic receptor family of G protein-coupled receptors that bind to extracellular nucleotides and nucleosides and mediate cellular responses. This receptor binds to UDP sugars and mediates the release of interleukin-8.
Clinical significance[edit | edit source]
Mutations in the P2RY6 gene have been associated with various diseases, including autoimmune diseases, cancer, and inflammatory diseases. The receptor has been found to be overexpressed in certain types of cancer, suggesting a role in tumor progression.
Research[edit | edit source]
Research into the P2RY6 gene and its associated protein is ongoing, with studies focusing on its role in inflammation, cancer progression, and potential as a therapeutic target.
See also[edit | edit source]
References[edit | edit source]
External links[edit | edit source]
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Contributors: Prab R. Tumpati, MD