PD-102,807

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PD-102,807 is a chemical compound that is used in scientific research. It is a selective antagonist for the muscarinic acetylcholine receptor M4.

Chemistry[edit | edit source]

PD-102,807 is a synthetic compound. It is part of the quinuclidine class of compounds, which are bicyclic amines. The compound is often used in its hydrochloride salt form.

Pharmacology[edit | edit source]

PD-102,807 acts as a selective antagonist at the M4 subtype of the muscarinic acetylcholine receptors. These receptors are a type of G protein-coupled receptor that respond to the neurotransmitter acetylcholine. Antagonists for these receptors block the action of acetylcholine, preventing it from activating the receptor.

Use in Research[edit | edit source]

PD-102,807 is used in research to help understand the role of the M4 muscarinic acetylcholine receptor in the body and in various diseases. For example, it has been used in studies investigating the role of these receptors in Parkinson's disease and schizophrenia.

See Also[edit | edit source]

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Contributors: Prab R. Tumpati, MD