Pandoraea sputorum

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Pandoraea sputorum is a bacterial species belonging to the genus Pandoraea. It is a Gram-negative, rod-shaped, and non-spore-forming bacterium. This species is known to be associated with lung infections, particularly in patients with cystic fibrosis.

Taxonomy[edit | edit source]

The genus Pandoraea was first proposed in 2000 by Coenye et al., and Pandoraea sputorum was first isolated and described in 2001. The genus name Pandoraea is derived from Greek mythology, referencing Pandora, the first woman on earth who opened a forbidden box out of curiosity and released all evils into the world, symbolizing the unexpected and potentially harmful nature of this bacterial genus.

Characteristics[edit | edit source]

Pandoraea sputorum is a aerobic bacterium, meaning it requires oxygen to grow. It is oxidase positive and can grow at temperatures ranging from 25 to 42 degrees Celsius. The bacterium is capable of nitrate reduction, urease production, and denitrification.

Pathogenicity[edit | edit source]

Pandoraea sputorum has been identified in the sputum of patients with cystic fibrosis, a genetic disorder that affects the lungs and digestive system. The bacterium is resistant to many commonly used antibiotics, making infections difficult to treat. However, the exact role of Pandoraea sputorum in disease progression and its overall impact on patient health is still under investigation.

Treatment[edit | edit source]

Due to its resistance to many antibiotics, treatment of Pandoraea sputorum infections can be challenging. Current treatment strategies often involve a combination of antibiotics, but the effectiveness of these treatments varies. Research into new treatment options, including the development of new antibiotics and alternative therapies, is ongoing.

See also[edit | edit source]

References[edit | edit source]

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Contributors: Prab R. Tumpati, MD