Parasexual cycle

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Parasexual Cycle

The parasexual cycle is a non-sexual mechanism of genetic recombination that occurs in certain fungi, bacteria, and protozoa. This process was first described by Guido Pontecorvo in 1956 while studying the fungus Aspergillus nidulans.

Overview[edit | edit source]

The parasexual cycle is an alternative to sexual reproduction for organisms that do not have a sexual cycle or in conditions where sexual reproduction is not favored. It involves the processes of mitosis, nuclear fusion, and chromosome loss, resulting in offspring with a combination of the parents' genetic material.

Process[edit | edit source]

The parasexual cycle begins with the fusion of two genetically different cells, a process known as heterokaryosis. This results in a heterokaryotic cell containing two distinct nuclei. The nuclei then undergo mitosis independently, creating a cell with multiple nuclei.

Following mitosis, the nuclei may fuse in a process called nuclear fusion or karyogamy, resulting in a diploid cell. This cell contains two copies of each chromosome, one from each parent.

The final stage of the parasexual cycle is chromosome loss, where the diploid cell loses chromosomes during mitosis until it returns to a haploid state. This process is random, meaning the resulting cell may contain any combination of the original parents' chromosomes.

Significance[edit | edit source]

The parasexual cycle allows for genetic recombination in organisms that do not undergo sexual reproduction. This can increase genetic diversity, which can enhance survival in changing environments. It also allows for the study of genetic phenomena such as recombination, mutation, and segregation in organisms that do not have a sexual cycle.

See also[edit | edit source]

Parasexual cycle Resources
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Contributors: Prab R. Tumpati, MD