Parasitic infections

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Entamoeba histolytica life cycle

Parasitic infections refer to diseases caused by parasitic organisms that live and reproduce within or on a host organism, usually causing harm. Parasites can be broadly categorized into protozoa (single-celled organisms) and helminths (worm-like parasites). These infections are a significant cause of morbidity and mortality worldwide, especially in tropical and subtropical regions.

Introduction[edit | edit source]

Strongyloides Storcoralis Lifecycle Diagram

Parasitic infections can affect almost any part of the body and are often associated with poor sanitation, contaminated food or water, and vectors like mosquitoes. Many parasites have complex life cycles that involve multiple hosts, stages, and transmission routes.

Classification[edit | edit source]

Parasitic infections can be classified based on the type of organism:

  • Protozoa: Single-celled organisms that often infect the gastrointestinal tract, blood, or tissue.
  • Example: Plasmodium spp. (causes malaria), Giardia lamblia (causes giardiasis)
  • Helminths: Worm-like organisms which can be further categorized into:
    • Nematodes (roundworms): Such as Ascaris lumbricoides and Enterobius vermicularis.
    • Trematodes (flukes): Such as Schistosoma spp.
    • Cestodes (tapeworms): Such as Taenia solium and Echinococcus granulosus.
  • Ectoparasites: Parasites that live on the surface of the host.
    • Example: Lice, ticks, and mites.

Clinical Presentation[edit | edit source]

The symptoms of parasitic infections vary widely depending on the organism, location, and intensity of the infection. Some common presentations include:

  • Gastrointestinal disturbances: Diarrhea, abdominal pain, nausea, or vomiting.
  • Fever and systemic symptoms: Seen in infections like malaria.
  • Skin manifestations: Rashes, itching, or subcutaneous nodules.
  • Organ-specific symptoms: Such as hepatosplenomegaly in schistosomiasis or neurocysticercosis in tapeworm infections.

Many parasitic infections can also remain asymptomatic, especially in endemic areas where repeated exposures can lead to partial immunity.

Diagnosis[edit | edit source]

Diagnostic methods vary based on the suspected parasite:

  • Microscopic examination: Detection of parasites, eggs, or cysts in samples such as stool, urine, or blood.
  • Molecular tests: PCR for detecting parasite DNA.
  • Serology: Detection of antibodies against the parasite.
  • Imaging: X-rays, CT scans, or ultrasounds to detect organ damage or large parasites.

Treatment[edit | edit source]

Treatment often involves anti-parasitic medications tailored to the specific organism, alongside supportive care. Some commonly used drugs include:

  • Metronidazole for protozoal infections.
  • Praziquantel for trematode and cestode infections.
  • Albendazole or mebendazole for nematode infections.

Prevention[edit | edit source]

Prevention strategies depend on the type and mode of transmission of the parasite:

  • Improved sanitation and access to clean water.
  • Use of insect repellents, bed nets, and appropriate clothing in areas with vector-borne transmission.
  • Regular deworming in endemic areas.
  • Proper food storage, preparation, and cooking.

List of parasitic infections[edit | edit source]

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  • nonpathogenic intestinal amebae infection -

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Conclusions[edit | edit source]

Parasitic infections remain a significant global health challenge, particularly in resource-limited settings. Improved diagnostics, effective treatments, and prevention strategies are crucial in managing and reducing the burden of these infections.

See Also[edit | edit source]

External Links[edit | edit source]

Parasitic infections Resources
Wikipedia

A-Z index of infectious diseases | Glossary of infection control | Glossary of vaccines



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Contributors: Prab R. Tumpati, MD