Parasubiculum
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System | Limbic system |
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The parasubiculum is a component of the hippocampal formation located in the medial temporal lobe of the brain. It is situated adjacent to the subiculum and plays a role in the processing of spatial information and memory.
Structure[edit | edit source]
The parasubiculum is part of the parahippocampal gyrus and is located between the presubiculum and the entorhinal cortex. It is characterized by a distinct cellular architecture that contributes to its function in the limbic system.
Function[edit | edit source]
The parasubiculum is involved in the processing of spatial navigation and memory encoding. It receives input from the entorhinal cortex and projects to the hippocampus, playing a crucial role in the hippocampal formation's ability to integrate sensory information and memory processing.
Connections[edit | edit source]
The parasubiculum has extensive connections with other parts of the hippocampal formation, including the subiculum, presubiculum, and entorhinal cortex. These connections facilitate the flow of information necessary for memory consolidation and spatial orientation.
Clinical significance[edit | edit source]
Dysfunction or damage to the parasubiculum can contribute to memory disorders and spatial disorientation, which are often observed in conditions such as Alzheimer's disease and other forms of dementia.
Research[edit | edit source]
Recent studies have focused on the role of the parasubiculum in neuroplasticity and its potential involvement in neurodegenerative diseases. Understanding its function and connections may provide insights into therapeutic targets for cognitive disorders.
See also[edit | edit source]
References[edit | edit source]
External links[edit | edit source]
- [Link to relevant neuroscience resources]
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Contributors: Prab R. Tumpati, MD