Parvocellular reticular nucleus

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Parvocellular Reticular Nucleus[edit | edit source]

The Parvocellular Reticular Nucleus (PRN) is a component of the brainstem that plays a significant role in the regulation of motor control. It is part of the reticular formation, a set of interconnected nuclei that are located throughout the brainstem.

The location of the Parvocellular Reticular Nucleus in the brainstem (highlighted).

Structure[edit | edit source]

The Parvocellular Reticular Nucleus is located in the medulla oblongata, the lower half of the brainstem. It is situated close to the midline, adjacent to the paramedian reticular nucleus. The PRN is characterized by its small, densely packed cells, from which it derives its name - 'parvocellular' means 'small cell'.

Function[edit | edit source]

The PRN is involved in the control of eye movement and gaze. It receives input from the superior colliculus, a structure in the midbrain that processes visual information. The PRN also sends projections to the spinal cord, influencing motor control.

Clinical Significance[edit | edit source]

Damage to the PRN can result in a range of motor control disorders, including ataxia and dysmetria. It may also contribute to the development of certain neurodegenerative diseases, such as Parkinson's disease.

See Also[edit | edit source]

References[edit | edit source]

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Contributors: Prab R. Tumpati, MD