Cadaverine

Cadaverine is a foul-smelling diamine compound produced by protein hydrolysis during putrefaction of animal tissue. It is a toxic diamine with the formula NH₂(CH₂)₅NH₂. Cadaverine is also known as 1,5-pentanediamine and is similar in structure to putrescine.

Production and Occurrence

Cadaverine is produced by the bacterial decarboxylation of the amino acid lysine during the decomposition of animal tissue. It is commonly found in decaying flesh and contributes to the characteristic odor of putrefaction. The compound is also present in small quantities in living organisms and is involved in various biological processes.

Chemical Properties

Cadaverine is a colorless, syrupy liquid with an unpleasant odor. It is soluble in water and has a boiling point of 178°C. The chemical structure of cadaverine consists of a chain of five methylene groups (CH₂) flanked by two amino groups (NH₂).

Biological Role

In living organisms, cadaverine is involved in cellular processes such as cell growth and differentiation. It is also a precursor for the synthesis of other biologically important molecules. However, in high concentrations, cadaverine can be toxic and is associated with the unpleasant odors of decaying tissue.

Applications

Cadaverine has applications in various fields, including:

• Forensic science: Used as an indicator of the time of death in forensic investigations.
• Biotechnology: Utilized in the production of polyamides and other polymers.
• Medical research: Studied for its role in various physiological and pathological processes.

Related Compounds

Cadaverine is structurally related to other biogenic amines such as putrescine, spermidine, and spermine. These compounds are collectively known as polyamines and play crucial roles in cellular functions.

See Also

• Putrescine
• Polyamines
• Forensic science
• Biotechnology