Perfluorohexyloctane
What is Perfluorohexyloctane?[edit | edit source]
- Perfluorohexyloctane (Miebo), is a semifluorinated alkane, contains 6 perfluorinated carbon atoms and 8 hydrogenated carbon atoms.
What are the uses of this medicine?[edit | edit source]
Perfluorohexyloctane (Miebo), is used for the treatment of the signs and symptoms of dry eye disease (DED).
How does this medicine work?[edit | edit source]
- Perfluorohexyloctane, a semifluorinated alkane, contains 6 perfluorinated carbon atoms and 8 hydrogenated carbon atoms. Perfluorohexyloctane forms a monolayer at the air-liquid interface of the tear film which can be expected to reduce evaporation.
- The exact mechanism of action for Miebo in DED is not known.
Who Should Not Use this medicine ?[edit | edit source]
- This medicine have no usage limitations.
What drug interactions can this medicine cause?[edit | edit source]
- Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.
- Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
Is this medicine FDA approved?[edit | edit source]
- Perfluorohexyloctane was approved for medical use in the United States in May 2023.
How should this medicine be used?[edit | edit source]
Recommended dosage:
- Instill one drop of Miebo four times daily into each eye.
Administration:
- Miebo (perfluorohexyloctane ophthalmic solution) is a sterile, clear and colorless liquid containing perfluorohexyloctane, for topical ophthalmic use.
- Advise patients to instill one drop of Miebo four times daily into each eye as depicted.
- Advise patients that contact lenses should be removed prior to and for at least 30 minutes after administration of Miebo.
What are the dosage forms and brand names of this medicine?[edit | edit source]
This medicine is available in fallowing doasage form:
- As Ophthalmic solution: 100% perfluorohexyloctane.
This medicine is available in fallowing brand namesː
- Miebo
What side effects can this medication cause?[edit | edit source]
The most common side effects of this medicine include:
- blurred vision
- conjunctival redness
What special precautions should I follow?[edit | edit source]
- Miebo should not be administered while wearing contact lenses. Advise patients that contact lenses should be removed prior to and for at least 30 minutes after administration of Miebo.
- There are no data on the presence of perfluorohexyloctane in human milk, the effects on the breastfed infant, or the effects on milk production.
What to do in case of emergency/overdose?[edit | edit source]
- In case of overdose, call the poison control helpline of your country. In the United States, call 1-800-222-1222.
- Overdose related information is also available online at poisonhelp.org/help.
- In the event that the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services. In the United States, call 911.
Can this medicine be used in pregnancy?[edit | edit source]
- There are no adequate and well controlled studies with Miebo in pregnant women.
Can this medicine be used in children?[edit | edit source]
- The safety and effectiveness of Miebo in pediatric patients below the age of 18 years have not been established.
What are the active and inactive ingredients in this medicine?[edit | edit source]
Active ingredient:
- Perfluorohexyloctane
Inactive ingredients:
- none
Who manufactures and distributes this medicine?[edit | edit source]
Distributed by:
- Bausch & Lomb Americas Inc.
- Bridgewater, NJ USA
- Miebo is a trademark of Bausch & Lomb Incorporated or its affiliates.
What should I know about storage and disposal of this medication?[edit | edit source]
- Store Miebo at 15ºC to 25ºC (59ºF to 77ºF).
- After opening, Miebo can be used until the expiration date on the bottle.
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