Perfluoromethyldecalin

From WikiMD's Food, Medicine & Wellness Encyclopedia

Perfluoromethyldecalin (PFMD), also known as Perfluorodecalin or Perflubron, is a fluorocarbon, a type of compound consisting of carbon and fluorine atoms. It is a colorless, odorless liquid that is used in a variety of medical and scientific applications due to its unique properties.

Chemical Properties[edit | edit source]

Perfluoromethyldecalin is a fully fluorinated compound, meaning all of its hydrogen atoms have been replaced with fluorine atoms. This gives it a number of unique properties, including high density, low viscosity, and excellent thermal stability. It is also chemically and biologically inert, meaning it does not react with other substances or cause biological reactions.

Medical Applications[edit | edit source]

Perfluoromethyldecalin has a number of medical applications due to its unique properties. It is used in liquid breathing systems, where it acts as an oxygen carrier, allowing oxygen to be dissolved in the liquid and then absorbed by the body. This can be used in the treatment of conditions such as acute respiratory distress syndrome (ARDS) and premature birth.

It is also used in eye surgery, where it acts as a temporary filler to stabilize the retina during surgery. This is particularly useful in cases of retinal detachment, where the retina has become separated from the back of the eye.

In addition, perfluoromethyldecalin is used in medical imaging, where it can enhance the contrast of images and improve the visibility of certain structures or areas of the body.

Scientific Research[edit | edit source]

Perfluoromethyldecalin is also used in scientific research, particularly in the field of nanotechnology. It is used as a solvent in the production of nanoparticles, due to its ability to dissolve a wide range of substances.

Safety[edit | edit source]

While perfluoromethyldecalin is generally considered safe for use in medical applications, it can cause side effects in some cases. These can include eye irritation, skin irritation, and in rare cases, allergic reactions. As with any medical treatment, the potential benefits must be weighed against the potential risks.


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Contributors: Prab R. Tumpati, MD