Phaclofen

From WikiMD's WELLNESSPEDIA

Phaclofen is a GABAB receptor antagonist drug that was first described in the literature in 1981. It is used in scientific research and has no known therapeutic use in humans.

History[edit]

Phaclofen was first described in the literature in 1981. It was developed as a research tool for studying the GABAB receptor, a type of G protein-coupled receptor that is found in the brain and spinal cord. The GABAB receptor is involved in a variety of physiological processes, including inhibition of neuronal activity and modulation of neurotransmitter release.

Pharmacology[edit]

Phaclofen acts as an antagonist at the GABAB receptor, meaning that it blocks the action of the neurotransmitter gamma-aminobutyric acid (GABA) at this receptor. This makes it a useful tool for studying the role of the GABAB receptor in various physiological processes.

Research Use[edit]

Phaclofen has been used in a variety of research studies to investigate the role of the GABAB receptor in the brain and spinal cord. For example, it has been used to study the role of this receptor in pain perception, memory formation, and the regulation of mood and anxiety.

See Also[edit]

References[edit]


Stub icon

This WikiMD article can only be edited by registered and verified editors. You can log in or register.


  • Phaclofen
    Phaclofen

Sponsored Health Resource

W8MD weight loss success

W8MD Weight Loss, Sleep & MedSpa

Looking for physician-supervised weight loss, semaglutide, tirzepatide, or GLP-1 receptor agonist options? W8MD helps eligible patients in New York City, Brooklyn, New Jersey, Connecticut, Pennsylvania, Delaware, and greater Philadelphia with medical weight loss, sleep medicine, and long-term maintenance support.

GLP-1 specials: Affordable GLP-1 injections NYC and Philadelphia starting from $29.99/week and up for semaglutide with insurance accepted for qualifying visits, and $45/week and up for tirzepatide with insurance accepted for qualifying visits. Self-pay options start from $59.99/week and up for semaglutide and $69.99/week and up for tirzepatide.

Book a W8MD appointment · View GLP-1 specials

Paid promotional message. Eligibility, pricing, insurance coverage, medication availability, and results vary. Medical evaluation required.

Medical Disclaimer: WikiMD is for informational purposes only and is not a substitute for professional medical advice. Content may be inaccurate or outdated and should not be used for diagnosis or treatment. Always consult your healthcare provider for medical decisions. Verify information with trusted sources such as CDC.gov and NIH.gov. By using this site, you agree that WikiMD is not liable for any outcomes related to its content. See full disclaimer.

Credits:Most images are courtesy of Wikimedia commons, and templates, categories Wikipedia, licensed under CC BY SA or similar.

Retrieved from "https://wikimd.org/index.php?title=Phaclofen&oldid=6495955"