PharmGKB
PharmGKB is a comprehensive resource that provides information about how human genetic variation affects response to medications. It is a free, web-based tool developed by the Pharmacogenomics Knowledge Base (PharmGKB) team at Stanford University.
Overview[edit | edit source]
PharmGKB collects, curates and disseminates knowledge about the impact of human genetic variations on drug response. It provides information about Pharmacogenetic tests and Pharmacogenomic data, as well as clinical guidelines for pharmacogenomic testing and drug dosing.
Content[edit | edit source]
PharmGKB's content includes:
- Pharmacogenomic data: This includes information about genetic variations that affect drug response, such as Single Nucleotide Polymorphisms (SNPs), copy number variations (CNVs), and other types of genetic variations.
- Pharmacogenetic tests: PharmGKB provides information about pharmacogenetic tests that are available for clinical use. This includes information about the genes that are tested, the drugs that the tests are relevant for, and the clinical implications of the test results.
- Clinical guidelines: PharmGKB provides clinical guidelines for pharmacogenomic testing and drug dosing. These guidelines are developed by professional organizations and are based on the latest scientific evidence.
Usage[edit | edit source]
PharmGKB is used by researchers, clinicians, and others who are interested in pharmacogenomics. It is a valuable resource for those who are conducting research in this field, as well as for those who are using pharmacogenomic data in clinical practice.
See Also[edit | edit source]
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Contributors: Prab R. Tumpati, MD
