Pharmacodynamics
Pharmacodynamics is the study of how a drug affects an organism, whereas Pharmacokinetics is the study of how the organism affects the drug. Both together influence dosing, benefit, and adverse effects.
Mechanisms of action[edit | edit source]
Pharmacodynamics is sometimes abbreviated as "PD" and its effects are often classified as either therapeutic or toxic. Pharmacodynamics can be split into two areas: (1) effects on the body and (2) effects on microorganisms such as bacteria, viruses, and fungi.
Drug concentration and effect[edit | edit source]
The relationship between the concentration of a drug and the response of the organism plays a key role in pharmacodynamic interactions. This relationship represents the body's response to increasing doses of a drug.
Drug-receptor interactions[edit | edit source]
The interaction of a drug with its receptor is fundamental to its pharmacodynamic effect. The nature of this interaction can vary, and different drugs may have different affinities for the same receptor, leading to a range of effects.
Drug resistance[edit | edit source]
Drug resistance is a significant concern in pharmacodynamics, particularly in the treatment of infections and cancer. It occurs when an organism develops a reduced sensitivity or resistance to a drug.
See also[edit | edit source]
- Pharmacokinetics
- Pharmacology
- Pharmaceutics
- Pharmacognosy
- Pharmacy
- Medicinal chemistry
- Pharmacotherapy
- Toxicology
References[edit | edit source]
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