Phenazone
Phenazone (also known as antipyrine or analgesine) is an analgesic and antipyretic compound with the chemical formula C11H12N2O. It was first synthesized by Ludwig Knorr in 1887. Phenazone is derived from pyrazolone, with additional ketone and phenyl groups.
Etymology[edit | edit source]
The term "phenazone" is derived from the chemical structure of the compound, which consists of a phenyl group (from Greek phainein, meaning "to show") and a azo group (from Greek azo, meaning "nitrogen"). The suffix "-one" indicates the presence of a carbonyl group.
Pharmacology[edit | edit source]
Phenazone has analgesic (pain-relieving) and antipyretic (fever-reducing) properties. It is thought to act by inhibiting the production of prostaglandins, which are involved in the body's inflammatory response. Phenazone is rapidly absorbed from the gastrointestinal tract and is metabolized in the liver.
Medical uses[edit | edit source]
Phenazone is used to treat pain and fever. It is often combined with other medications, such as caffeine, to enhance its effects. Phenazone has also been used in the treatment of rheumatic diseases and as a diagnostic tool in testing for deficiencies of certain enzymes in the body.
Side effects[edit | edit source]
Common side effects of phenazone include gastrointestinal upset, dizziness, and allergic reactions. In rare cases, it can cause serious side effects such as blood disorders and liver damage.
Related terms[edit | edit source]
- Analgesic: A type of medication used to relieve pain.
- Antipyretic: A type of medication used to reduce fever.
- Prostaglandin: A group of compounds with various hormone-like effects, including the promotion of inflammation.
- Rheumatic disease: A group of disorders affecting the joints and connective tissue.
| Phenazone Resources | |
|---|---|
|
 |
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
