Phenolphthalein

From WikiMD's Wellness Encyclopedia

Phenolphthalein is a chemical compound often used as a pH indicator in titrations. For this purpose, it turns colorless in acidic solutions and pink in basic solutions. It belongs to the class of compounds known as phthaleins.

Chemical Properties[edit | edit source]

Phenolphthalein is a weak acid, which can lose H+ ions in solution. The phenolphthalein molecule is colorless, and the phenolphthalein ion is pink. When a base is added to the phenolphthalein, the molecule ⇌ ions equilibrium shifts to the right, leading to more ionization as H+ ions are removed. This is predicted by Le Chatelier's principle.

Uses[edit | edit source]

Phenolphthalein is used in toys, for example as a component of disappearing inks, and is used in some forensic blood tests. The compound is also commonly used in various laboratory settings for titrations of acid-base reactions.

Health Effects[edit | edit source]

Phenolphthalein has been used for over a century as a laxative, but is not sold in the U.S. because it is carcinogenic. It was also used in over-the-counter products, such as Ex-Lax, until 1999, when the FDA reclassified the drug as "not generally recognized as safe and effective".

See Also[edit | edit source]

References[edit | edit source]

Phenolphthalein Resources

Contributors: Prab R. Tumpati, MD