Phenylbiguanide

Phenylbiguanide is a compound that is often used in scientific research, particularly in studies related to the cardiovascular system and serotonin receptors. It is known to stimulate 5-HT3 receptors, which are a type of serotonin receptor found primarily in the brain and in the gastrointestinal tract.

Chemical Structure

Phenylbiguanide has a chemical structure that includes a phenyl ring and a biguanide group. The phenyl ring is a functional group of the form -C6H5, which consists of a benzene ring minus one hydrogen atom. The biguanide group is a functional group consisting of two guanidine groups, with the formula -NHC(=NH)NHC(NH2)2.

Uses in Research

Phenylbiguanide is often used in research due to its ability to stimulate 5-HT3 receptors. This makes it useful in studies investigating the role of these receptors in various physiological processes. For example, it has been used in studies looking at the role of 5-HT3 receptors in the regulation of the cardiovascular system, as well as in studies investigating the role of these receptors in the gastrointestinal tract.

Pharmacological Effects

When phenylbiguanide is administered, it can have a number of pharmacological effects. These are primarily due to its stimulation of 5-HT3 receptors. For example, it can cause a decrease in heart rate and blood pressure, as well as an increase in gastric motility. These effects can be useful in the study of various diseases and conditions, such as hypertension and gastrointestinal disorders.

Safety and Toxicity

Like all compounds, phenylbiguanide has the potential to be toxic if not handled correctly. It is important that it is used in a controlled environment, and that appropriate safety measures are taken. This includes the use of personal protective equipment, and the proper disposal of any waste materials.

Phenylbiguanide Resources
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