Phenylephrine/ketorolac

Phenylephrine/Ketorolac

Phenylephrine/Ketorolac is a combination medication used in the field of ophthalmology to maintain pupil size by preventing intraoperative miosis (pupil constriction) and reducing postoperative ocular pain during cataract surgery or intraocular lens replacement.

Composition[edit | edit source]

This medication is a combination of two active ingredients: Phenylephrine and Ketorolac. Phenylephrine is a selective alpha-1 adrenergic receptor agonist used for dilation of the pupil. It works by constricting the blood vessels in the eye, thereby reducing the amount of fluid that can drain out of the eye. Ketorolac is a nonsteroidal anti-inflammatory drug (NSAID) that works by blocking the production of certain natural substances in your body to reduce pain and swelling.

Indications[edit | edit source]

Phenylephrine/Ketorolac is indicated for the maintenance of mydriasis (pupil dilation) during cataract surgery or intraocular lens replacement and for the reduction of postoperative ocular pain.

Contraindications[edit | edit source]

This medication is contraindicated in patients with known hypersensitivity to any of its components, or to other NSAIDs, and in patients with asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs.

Side Effects[edit | edit source]

Common side effects of Phenylephrine/Ketorolac include increased intraocular pressure, posterior capsule opacification, eye inflammation, and eye pain. Serious side effects may include slow or uneven heart rate, severe headache, buzzing in your ears, anxiety, confusion, shortness of breath, and severe nausea.

Interactions[edit | edit source]

Phenylephrine/Ketorolac may interact with other medications, including blood thinners, steroids, and other NSAIDs. It is important to inform your healthcare provider of all medications you are currently taking.

Dosage[edit | edit source]

The recommended dose of Phenylephrine/Ketorolac is one drop instilled into the affected eye(s) three times in the hour before surgery.

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