Photopheresis

From WikiMD's Wellness Encyclopedia

Photopheresis is a type of apheresis and photodynamic therapy in which blood is treated with a photosensitizing agent and subsequently irradiated with specific wavelengths of light to treat a variety of disorders.

History[edit | edit source]

The technique was first introduced by Richard L. Edelson of Yale University in 1987 for the treatment of cutaneous T-cell lymphoma (CTCL). Since then, it has been used to treat a variety of other conditions.

Procedure[edit | edit source]

In photopheresis, the patient's blood is first drawn and separated into its components. The white blood cells are then mixed with a photosensitizing agent, usually methoxsalen, and exposed to ultraviolet A (UVA) light. The treated cells are then returned to the patient. The entire process takes about two to three hours and is usually performed on an outpatient basis.

Uses[edit | edit source]

Photopheresis has been used to treat a variety of conditions, including:

Side Effects[edit | edit source]

Possible side effects of photopheresis include:

See Also[edit | edit source]

References[edit | edit source]


Photopheresis Resources

Contributors: Prab R. Tumpati, MD