Photopheresis
Photopheresis is a type of apheresis and photodynamic therapy in which blood is treated with a photosensitizing agent and subsequently irradiated with specific wavelengths of light to treat a variety of disorders.
History[edit | edit source]
The technique was first introduced by Richard L. Edelson of Yale University in 1987 for the treatment of cutaneous T-cell lymphoma (CTCL). Since then, it has been used to treat a variety of other conditions.
Procedure[edit | edit source]
In photopheresis, the patient's blood is first drawn and separated into its components. The white blood cells are then mixed with a photosensitizing agent, usually methoxsalen, and exposed to ultraviolet A (UVA) light. The treated cells are then returned to the patient. The entire process takes about two to three hours and is usually performed on an outpatient basis.
Uses[edit | edit source]
Photopheresis has been used to treat a variety of conditions, including:
- Cutaneous T-cell lymphoma
- Graft-versus-host disease
- Systemic sclerosis
- Rheumatoid arthritis
- Crohn's disease
- Multiple sclerosis
- Type 1 diabetes
Side Effects[edit | edit source]
Possible side effects of photopheresis include:
See Also[edit | edit source]
References[edit | edit source]
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