Pimeclone

Pimeclone

Pimeclone is a sedative and anxiolytic drug in the cyclopyrrolone family, which includes similar drugs such as zopiclone and eszopiclone. It was developed in the late 1980s by the French pharmaceutical company Sanofi-Aventis and is used primarily in Europe for the treatment of insomnia and other sleep disorders.

Pharmacology

Pimeclone acts as a full agonist at the benzodiazepine receptor complex, producing effects similar to those of benzodiazepines, such as sedation, muscle relaxation, and anxiolysis. It has a high bioavailability and a short half-life, making it suitable for short-term treatment of acute insomnia.

Medical uses

Pimeclone is primarily used for the short-term treatment of insomnia. It is also used off-label for the treatment of certain forms of anxiety, particularly those associated with sleep disturbances. Due to its short half-life, it is not recommended for long-term use or for the treatment of chronic insomnia.

Side effects

Common side effects of Pimeclone include drowsiness, dizziness, and impaired coordination. Less common side effects include memory impairment, hallucinations, and changes in mood or behavior. Long-term use can lead to tolerance, dependence, and withdrawal symptoms upon discontinuation.

See also

• Zopiclone
• Eszopiclone
• Cyclopyrrolones
• Benzodiazepine