Pimeclone
Pimeclone is a sedative and anxiolytic drug in the cyclopyrrolone family, which includes similar drugs such as zopiclone and eszopiclone. It was developed in the late 1980s by the French pharmaceutical company Sanofi-Aventis and is used primarily in Europe for the treatment of insomnia and other sleep disorders.
Pharmacology[edit | edit source]
Pimeclone acts as a full agonist at the benzodiazepine receptor complex, producing effects similar to those of benzodiazepines, such as sedation, muscle relaxation, and anxiolysis. It has a high bioavailability and a short half-life, making it suitable for short-term treatment of acute insomnia.
Medical uses[edit | edit source]
Pimeclone is primarily used for the short-term treatment of insomnia. It is also used off-label for the treatment of certain forms of anxiety, particularly those associated with sleep disturbances. Due to its short half-life, it is not recommended for long-term use or for the treatment of chronic insomnia.
Side effects[edit | edit source]
Common side effects of Pimeclone include drowsiness, dizziness, and impaired coordination. Less common side effects include memory impairment, hallucinations, and changes in mood or behavior. Long-term use can lead to tolerance, dependence, and withdrawal symptoms upon discontinuation.
See also[edit | edit source]
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