Poikiloderma
Poikiloderma | |
---|---|
Synonyms | |
Pronounce | N/A |
Specialty | N/A |
Symptoms | Skin atrophy, telangiectasia, hyperpigmentation, hypopigmentation |
Complications | |
Onset | |
Duration | |
Types | N/A |
Causes | Genetic disorders, environmental factors |
Risks | |
Diagnosis | Clinical examination, biopsy |
Differential diagnosis | Lupus erythematosus, scleroderma |
Prevention | N/A |
Treatment | Sun protection, topical treatments |
Medication | |
Prognosis | |
Frequency | |
Deaths | N/A |
Poikiloderma is a condition characterized by changes in the skin, including atrophy, telangiectasia, and variations in pigmentation such as hyperpigmentation and hypopigmentation. It is often a result of genetic disorders or environmental factors.
Signs and Symptoms[edit | edit source]
Poikiloderma presents with a combination of skin changes:
- Skin atrophy - thinning of the skin
- Telangiectasia - visible small blood vessels
- Hyperpigmentation - darkening of the skin
- Hypopigmentation - lightening of the skin
Causes[edit | edit source]
The causes of poikiloderma can be varied and include:
- Genetic disorders such as Rothmund-Thomson syndrome, Bloom syndrome, and Dyskeratosis congenita.
- Environmental factors like chronic sun exposure, which can lead to actinic damage.
Diagnosis[edit | edit source]
Diagnosis of poikiloderma is primarily clinical, based on the appearance of the skin. A biopsy may be performed to rule out other conditions and confirm the diagnosis.
Differential Diagnosis[edit | edit source]
Conditions that may present similarly to poikiloderma include:
Treatment[edit | edit source]
Management of poikiloderma focuses on:
- Sun protection to prevent further damage
- Topical treatments such as retinoids or steroids to improve skin appearance
See Also[edit | edit source]
References[edit | edit source]
External Links[edit | edit source]
- [Poikiloderma at DermNet NZ](https://dermnetnz.org/topics/poikiloderma/)
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Contributors: Prab R. Tumpati, MD