Poikiloderma

From WikiMD's Wellness Encyclopedia

People with varying manifestations of poikiloderma
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Poikiloderma is a skin condition that consists of areas of hypopigmentation, hyperpigmentation, telangiectasias and atrophy. Poikiloderma of Civatte is most frequently seen on the chest or the neck, characterized by red colored pigment on the skin that is commonly associated with sun damage.[1]

Types[edit | edit source]

Causes[edit | edit source]

  • Congenital
  1. Rothmund-Thompson syndrome
  2. Dyskeratosis congenita
  3. Mendes da Costa syndrome
  • Other hereditary causes
  1. Degos-Touraine syndrome
  2. Diffuse and macular atrophic dermatosis
  3. Hereditary sclerosing poikiloderma of weary
  4. Kindler syndrome
  5. Weary-Kindler syndrome
  6. Xeroderma pigmentosum
  • Acquired
  1. Injury to cold, heat, ionizing radiation, exposure to sensitizing chemicals
  2. Lichen planus
  3. Dermatomyositis
  4. Lupus erythematosus
  5. Systemic sclerosis
  6. Cutaneous T cell lymphomas

Pathogenesis[edit | edit source]

The exact cause of poikiloderma of Civatte is unknown; however, extended sun exposure, namely the ultraviolet light emitted by the sun, is the primary factor.[2]

Diagnosis[edit | edit source]


Treatment[edit | edit source]

Albeit difficult, treatment of poikiloderma of Civatte involves the delivery of multiple wavelengths of intense pulsed light (IPL) to the affected area.[3]

See also[edit | edit source]

References[edit | edit source]

  1. American Osteopathic College of Dermatology "Dermatologic Disease Database", aocd.org, referenced July 22, 2011.
  2. PubMed.gov "Treatment of poikiloderma of Civatte with an intense pulsed light source", PubMed.gov, referenced July 22, 2011.



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