Portogloboviridae
Portogloboviridae is a family of viruses in the order Picornavirales. Viruses in Portogloboviridae are enveloped, with icosahedral and Round geometries. The diameter is around 30-35 nm. Genomes are linear and non-segmented, around 7.3-7.5kb in length.
Taxonomy[edit | edit source]
The family Portogloboviridae includes the following genera:
Structure[edit | edit source]
Viruses in Portogloboviridae are enveloped, with icosahedral and spherical geometries, and T=pseudo3 symmetry. The diameter is around 30-35 nm. The genome is linear, around 7.3-7.5 kb in length. The genome codes for proteins in the following order: VPg+5'UTRIRES-II[1AB-1C-1D/2AH-box/NC-2B-2C/3A-3B-3C-3D]3'UTR-poly(A).
Life Cycle[edit | edit source]
Viral replication is cytoplasmic. Entry into the host cell is achieved by attachment of the virus to host receptors, which mediates endocytosis. Replication follows the positive stranded RNA virus replication model. Positive stranded RNA virus transcription is the method of transcription. The virus exits the host cell by lysis, and viroporins. Humans and bats serve as the natural host.
Clinical[edit | edit source]
The viruses in the family Portogloboviridae are associated with respiratory and gastrointestinal diseases in humans. They are also known to cause diseases in bats.
References[edit | edit source]
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