Pozanicline
An article about the drug Pozanicline
Overview[edit | edit source]
Pozanicline is a pharmaceutical compound that acts as a partial agonist at the nicotinic acetylcholine receptors. It is primarily investigated for its potential use in treating cognitive disorders and nicotine addiction.
Mechanism of Action[edit | edit source]
Pozanicline binds to the nicotinic acetylcholine receptors, which are a type of ligand-gated ion channel found in the central nervous system. By acting as a partial agonist, Pozanicline can modulate the activity of these receptors, leading to changes in neurotransmitter release and synaptic plasticity. This modulation is thought to enhance cognitive function and reduce the craving for nicotine in individuals with nicotine dependence.
Pharmacokinetics[edit | edit source]
Pozanicline is administered orally and is absorbed through the gastrointestinal tract. It undergoes hepatic metabolism and is excreted primarily through the renal system. The drug has a moderate half-life, allowing for once or twice daily dosing.
Clinical Applications[edit | edit source]
Pozanicline is being studied for its potential benefits in treating conditions such as Alzheimer's disease, schizophrenia, and attention deficit hyperactivity disorder (ADHD). Its ability to reduce nicotine cravings also makes it a candidate for smoking cessation therapies.
Side Effects[edit | edit source]
Common side effects of Pozanicline include nausea, headache, and insomnia. More serious adverse effects are rare but can include seizures and cardiovascular events.
Research and Development[edit | edit source]
Research on Pozanicline is ongoing, with several clinical trials evaluating its efficacy and safety in various populations. The drug's development is part of a broader effort to find effective treatments for cognitive impairments and addiction.
Related pages[edit | edit source]
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates, categories Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
