Prallethrin

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Prallethrin[edit | edit source]

Prallethrin is a synthetic pyrethroid insecticide commonly used for controlling various household pests. It belongs to the pyrethroid class of chemicals, which are derived from natural compounds found in chrysanthemum flowers. Prallethrin is known for its effectiveness against a wide range of insects, including mosquitoes, flies, cockroaches, and ants.

Chemical Properties[edit | edit source]

Prallethrin is chemically known as (RS)-2-methyl-4-oxo-3-(2-propynyl)cyclopent-2-enyl (1R)-cis, trans-chrysanthemate. It is a yellowish liquid with a faint odor. Prallethrin is insoluble in water but soluble in organic solvents such as ethanol and acetone. It is stable under normal conditions but can degrade when exposed to sunlight and high temperatures.

Mode of Action[edit | edit source]

Prallethrin acts as a neurotoxin, targeting the nervous system of insects. It disrupts the normal functioning of nerve cells by binding to sodium channels, which are responsible for transmitting electrical signals. This interference leads to paralysis and eventual death of the insect. Prallethrin has a quick knockdown effect, making it highly effective in controlling pests.

Uses[edit | edit source]

Prallethrin is widely used in household insecticides, mosquito coils, aerosol sprays, and vaporizers. It is effective in killing and repelling mosquitoes, flies, cockroaches, ants, and other crawling and flying insects. Prallethrin is commonly found in products designed for indoor use, such as insecticide sprays for kitchens, bedrooms, and living areas.

Safety Considerations[edit | edit source]

Prallethrin is considered to have low toxicity to humans and pets when used as directed. However, it is still important to follow safety precautions and read the product labels carefully. Direct skin contact with concentrated prallethrin may cause mild irritation, and inhalation of large amounts of the chemical may lead to respiratory discomfort. It is advisable to avoid spraying prallethrin near food, water sources, or areas where children and pets play.

Environmental Impact[edit | edit source]

Prallethrin is known to have a low environmental impact due to its rapid degradation in soil and water. It breaks down quickly under sunlight and microbial action, reducing the risk of long-term accumulation. However, it is still recommended to minimize its release into the environment by following proper disposal methods and avoiding excessive use.

References[edit | edit source]

1. PubChem: Prallethrin 2. National Pesticide Information Center: Prallethrin 3. National Center for Biotechnology Information: Pyrethroids and Their Effects on Human Health

See Also[edit | edit source]

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Contributors: Prab R. Tumpati, MD