Pravadoline
Pravadoline is a painkiller originally developed in the 1980s by the pharmaceutical industry. It is an analgesic that was specifically designed to be a non-steroidal anti-inflammatory drug (NSAID) with minimal gastrointestinal side effects.
History[edit | edit source]
Pravadoline was developed by the Upjohn Company in the 1980s. The drug was designed to be a new type of NSAID that would not have the gastrointestinal side effects associated with other NSAIDs. However, the drug was never marketed due to concerns about its potential for abuse.
Pharmacology[edit | edit source]
Pravadoline is a cannabinoid receptor agonist. It has analgesic effects and is used in the treatment of pain. The drug has a unique mechanism of action, as it does not act on the same receptors as other NSAIDs. Instead, it acts on the cannabinoid receptors in the brain, which are involved in the perception of pain.
Side Effects[edit | edit source]
Like all drugs, pravadoline has potential side effects. These can include nausea, vomiting, and dizziness. In rare cases, the drug can cause psychosis or other serious mental health problems.
Legal Status[edit | edit source]
Pravadoline is not currently approved for use in any country. It is classified as a Schedule I drug in the United States, which means it has a high potential for abuse and no accepted medical use.
See Also[edit | edit source]
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Contributors: Prab R. Tumpati, MD