Prednisolone tebutate
A synthetic glucocorticoid used in medicine
Overview[edit | edit source]
Prednisolone tebutate is a synthetic glucocorticoid used primarily for its anti-inflammatory and immunosuppressive properties. It is a derivative of prednisolone, a corticosteroid that is commonly used in the treatment of various inflammatory and autoimmune conditions.
Chemical Properties[edit | edit source]
Prednisolone tebutate is an ester of prednisolone, specifically the tebutate ester. This modification affects its pharmacokinetics, potentially altering its absorption, distribution, metabolism, and excretion compared to prednisolone itself.
Mechanism of Action[edit | edit source]
As a glucocorticoid, prednisolone tebutate works by binding to the glucocorticoid receptor, which then translocates to the cell nucleus and influences the transcription of specific genes. This results in the suppression of inflammatory cytokines and the inhibition of immune cell proliferation.
Clinical Uses[edit | edit source]
Prednisolone tebutate is used in the management of conditions such as:
Administration[edit | edit source]
The route of administration for prednisolone tebutate can vary depending on the specific formulation and the condition being treated. It may be administered orally, intravenously, or as a topical preparation.
Side Effects[edit | edit source]
Common side effects associated with glucocorticoids like prednisolone tebutate include:
- Hypertension
- Hyperglycemia
- Osteoporosis
- Increased risk of infection
Related Compounds[edit | edit source]
Related Pages[edit | edit source]
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Contributors: Prab R. Tumpati, MD
