Phenmetrazine

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Phenmetrazine is a stimulant drug that was previously used as an appetite suppressant, but has since been withdrawn from the market. It was initially marketed in the 1950s. Phenmetrazine was a problem drug, and is now a controlled substance in many countries due to its potential for addiction.

History[edit | edit source]

Phenmetrazine was first patented in Germany in 1952 by Boehringer-Ingelheim, with some pharmacological data appearing in the literature in 1954. It was the result of a search by the company for an anorectic drug to replace amphetamine, which was increasingly subject to abuse.

Pharmacology[edit | edit source]

Phenmetrazine acts as a norepinephrine-dopamine releasing agent (NDRA). It is also a metabolite of phendimetrazine, a more complex drug. Phenmetrazine stimulates the brain, increases heart rate, blood pressure and decreases appetite. Its effects can last from 3 to 4 hours.

Side Effects[edit | edit source]

Side effects of phenmetrazine include insomnia, hyperactivity, and restlessness. It can also cause palpitations, sweating, and dizziness. In severe cases, it can lead to psychosis.

Legal Status[edit | edit source]

Phenmetrazine is a controlled substance in many countries due to its potential for addiction. It is a Schedule II controlled substance in the United States.

See Also[edit | edit source]

References[edit | edit source]


Phenmetrazine Resources
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