Prevalence of rabies

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Prevalence of Rabies

Rabies is a viral disease that causes acute inflammation of the brain in humans and other warm-blooded animals. The disease is zoonotic, meaning it can be transmitted to humans from animals. The rabies virus is primarily spread through the saliva of infected animals, with dogs being the most common transmitter to humans. Despite being preventable through vaccination, rabies remains a significant public health concern in many parts of the world, particularly in Asia and Africa.

Epidemiology[edit | edit source]

The global prevalence of rabies is uneven, with over 95% of human deaths occurring in Asia and Africa. Countries with high rates of rabies transmission to humans include India, China, Vietnam, and parts of sub-Saharan Africa. In these regions, stray dogs are the primary reservoir and vector for the disease. In contrast, in the Americas and parts of Europe, rabies is more commonly found in wildlife such as bats, raccoons, skunks, and foxes.

Transmission[edit | edit source]

Rabies is transmitted through the exchange of blood or saliva from an infected animal, with bites being the most common method of transmission. However, transmission can also occur when infected saliva comes into contact with open wounds or mucous membranes. The rabies virus travels from the site of the bite or scratch through the peripheral nervous system until it reaches the brain, causing encephalitis.

Symptoms and Treatment[edit | edit source]

The initial symptoms of rabies are often nonspecific, such as fever, headache, and general weakness or discomfort. As the disease progresses, neurological symptoms develop, including insomnia, anxiety, confusion, paralysis, excitation, hallucinations, agitation, salivation, difficulty swallowing, and hydrophobia (fear of water). Once clinical symptoms appear, rabies is almost always fatal.

Pre-exposure prophylaxis (PEP) is recommended for individuals at high risk of exposure to rabies, such as veterinarians, animal handlers, and travelers to areas with high prevalence of rabies. PEP involves a series of rabies vaccinations before exposure. Post-exposure prophylaxis (PEP) is also highly effective in preventing the disease if administered promptly after exposure, before symptoms develop.

Prevention[edit | edit source]

Prevention of rabies involves controlling rabies in domestic and wild animals, vaccinating dogs, and providing education on avoiding animal bites. Public health campaigns aimed at vaccinating dogs have significantly reduced the prevalence of rabies in some parts of the world. In addition, educating communities about the importance of seeking immediate medical care after potential exposure to rabies is crucial in preventing the disease.

Conclusion[edit | edit source]

Rabies remains a significant public health challenge in many parts of the world. Efforts to reduce the prevalence of rabies focus on vaccination of animals, public health education, and provision of post-exposure prophylaxis to prevent the disease after potential exposure. Continued international cooperation and investment in rabies control programs are essential to reduce the global burden of this preventable disease.


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Contributors: Prab R. Tumpati, MD